Styrene Toxicology Cov Ntaub Ntawv

1. Mob toxicity
LD50: 1000mg / kg (rat qhov ncauj); 316mg / kg (nas qhov ncauj).
LC50: 24000mg/m3 (nas inhalation, 4h).
2. Kev khaus khaus
Luav percutaneous: 500mg, khaus khaus (qhib khaus khaus).
Luav per ocular: 100mg, mob heev.
3. Subacute thiab mob toxicity
Tsiaj txhu pom cov tsos mob ntawm qhov muag thiab qhov ntswg qhov muag ntawm 6.3 ~ 9.3g / m3, 7h ib hnub, 6 ~ 12 lub hlis, 130 ~ 264 zaug.
4. Mutagnicity
Microbial mutagenicity test: Salmonella typhimurium 1μmol / tais.
DNA inhibition: tib neeg Hela hlwb 28mmol / L.
Sister chromosome exchange: human inhalation 1204mg/m3 (5a).
5. Teratogenicity
Cov poj niam nas tau hnov ​​​​qhov ncauj qhov ncauj rau qhov tshuaj lom yam tsawg kawg nkaus (TDLo) ntawm 11470 mg / kg 6-15 hnub tom qab cev xeeb tub, uas ua rau muaj qhov tsis zoo ntawm cov kab mob urogenital.
6. Carcinogenicity
IARC carcinogenicity tshuaj xyuas: G2B, xav tias tib neeg carcinogen.